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Comparison of the plaque assay and 50% tissue culture infectious dose assay as methods for measuring filovirus infectivity

Smither, Sophie J., Lear-Rooney, Calli, Biggins, Julia, Pettitt, Jamie, Lever, Mark S., Olinger, Gene G.

Journal:

Journal of Virological Methods

Année:

2013

Langue:

english

Fichier:

PDF, 464 KB

english, 2013

Drug Targets in Infections with Ebola and Marburg Viruses

Gene, Olinger, Julia, Biggins, Vanessa, Melanson, Victoria, Wahl-Jensen, Thomas, Geisbert, Lisa, Hensley

Journal:

Infectious Disorders - Drug Targets(Formerly Current Drug Targets - Infectious Disorders)

Année:

2009

Langue:

english

Fichier:

PDF, 157 KB

english, 2009

Standardization of the Filovirus Plaque Assay for Use in Preclinical Studies

Shurtleff, Amy, Biggins, Julia, Keeney, Ashley, Zumbrun, Elizabeth, Bloomfield, Holly, Kuehne, Ana, Audet, Jennifer, Alfson, Kendra, Griffiths, Anthony, Olinger, Gene, Bavari, Sina

Journal:

Viruses

Année:

2012

Langue:

english

Fichier:

PDF, 292 KB

english, 2012

Potential Vaccines and Post-Exposure Treatments for Filovirus Infections

Friedrich, Brian M., Trefry, John C., Biggins, Julia E., Hensley, Lisa E., Honko, Anna N., Smith, Darci R., Olinger, Gene G.

Journal:

Viruses

Année:

2012

Langue:

english

Fichier:

PDF, 409 KB

english, 2012

Fighting Ebola with novel spore decontamination technologies for the military

Doona, Christopher J., Feeherry, Florence E., Kustin, Kenneth, Olinger, Gene G., Setlow, Peter, Malkin, Alexander J., Leighton, Terrance

Journal:

Frontiers in Microbiology

Année:

2015

Langue:

english

Fichier:

PDF, 7.49 MB

english, 2015

Zaire Ebola virus entry into human dendritic cells is insensitive to cathepsin L inhibition

Osvaldo Martinez, Joshua Johnson, Balaji Manicassamy, Lijun Rong, Gene G. Olinger, Lisa E. Hensley, Christopher F. Basler

Journal:

Cellular Microbiology

Année:

2010

Langue:

english

Fichier:

PDF, 311 KB

english, 2010

FGI-104: A Broad-Spectrum Small Molecule Inhibitor of Viral Infection

Michael Kinch, Abdul Yunus, Hanwen Mao, Calli Lear, Guangxiang Luo, Michael Murray, Zhuhui Huang, Zena Fesseha, Hanson Chen, Gene Olinger, Michael Goldblatt

Journal:

Antiviral Research

Année:

2009

Langue:

english

Fichier:

PDF, 88 KB

english, 2009

Inhibition of heat-shock protein 90 reduces Ebola virus replication

Darci R. Smith, Sarah McCarthy, Andrew Chrovian, Gene Olinger, Andrea Stossel, Thomas W. Geisbert, Lisa E. Hensley, John H. Connor

Journal:

Antiviral Research

Année:

2010

Langue:

english

Fichier:

PDF, 475 KB

english, 2010

CD8+ cellular immunity mediates rAd5 vaccine protection against Ebola virus infection of nonhuman primates

Sullivan, Nancy J, Hensley, Lisa, Asiedu, Clement, Geisbert, Thomas W, Stanley, Daphne, Johnson, Joshua, Honko, Anna, Olinger, Gene, Bailey, Michael, Geisbert, Joan B

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 569 KB

english, 2011

Filoviruses and the Balance of Innate, Adaptive, and Inflammatory Responses

Mohamadzadeh, Mansour, Chen, Lieping, Olinger, Gene G., Pratt, William D., Schmaljohn, Alan L.

Journal:

Viral Immunology

Année:

2006

Langue:

english

Fichier:

PDF, 357 KB

english, 2006

Control of Ebola virus infection in mice with recombinant human mannose-binding lectin: Requirement for C3

Ian Michelow, Gene Olinger, Gregory Spear, Louis Yantosca, Xin Ji, Kazue Takahashi, Emmett Schmidt

Journal:

Molecular Immunology

Année:

2008

Langue:

english

Fichier:

PDF, 77 KB

english, 2008

Cellular Factors Influence the Binding of HIV Type 1 to Cells

Olinger, Gene G., Saifuddin, Mohammed, Hart, Melanie L., Spear, Gregory T.

Journal:

AIDS Research and Human Retroviruses

Année:

2002

Langue:

english

Fichier:

PDF, 224 KB

english, 2002

Discovery of common marburgvirus protective epitopes in a BALB/c mouse model

Warren V Kalina, Kelly L Warfield, Gene G Olinger, Sina Bavari

Journal:

Virology Journal

Année:

2009

Langue:

english

Fichier:

PDF, 1.32 MB

english, 2009

Donor variability in HIV binding to peripheral blood mononuclear cells

Joshua J Anzinger, Gene G Olinger, Gregory T Spear

Journal:

Virology Journal

Année:

2008

Langue:

english

Fichier:

PDF, 217 KB

english, 2008

Post-exposure therapy of filovirus infections

Wong, Gary, Qiu, Xiangguo, Olinger, Gene G., Kobinger, Gary P.

Journal:

Trends in Microbiology

Année:

2014

Langue:

english

Fichier:

PDF, 295 KB

english, 2014

Pyridinyl imidazole inhibitors of p38 MAP kinase impair viral entry and reduce cytokine induction by Zaire ebolavirus in human dendritic cells

Johnson, Joshua C., Martinez, Osvaldo, Honko, Anna N., Hensley, Lisa E., Olinger, Gene G., Basler, Christopher F.

Journal:

Antiviral Research

Année:

2014

Langue:

english

Fichier:

PDF, 820 KB

english, 2014

The cyanobacterial lectin scytovirin displays potent in vitro and in vivo activity against Zaire Ebola virus

Garrison, Aura R., Giomarelli, Barbara G., Lear-Rooney, Calli M., Saucedo, Carrie J., Yellayi, Srikanth, Krumpe, Lauren R.H., Rose, Maura, Paragas, Jason, Bray, Mike, Olinger, Gene G., McMahon, James

Journal:

Antiviral Research

Année:

2014

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2014

Ebola Virus‐Like Particle–Based Vaccine Protects Nonhuman Primates against Lethal Ebola Virus Challenge

Warfield, Kelly L., Swenson, Dana L., Olinger, Gene G., Kalina, Warren V., Aman, M. Javad, Bavari, Sina

Journal:

The Journal of Infectious Diseases

Année:

2007

Langue:

english

Fichier:

PDF, 308 KB

english, 2007

Structures of protective antibodies reveal sites of vulnerability on Ebola virus

Murin, Charles D., Fusco, Marnie L., Bornholdt, Zachary A., Qiu, Xiangguo, Olinger, Gene G., Zeitlin, Larry, Kobinger, Gary P., Ward, Andrew B., Saphire, Erica Ollmann

Journal:

Proceedings of the National Academy of Sciences

Année:

2014

Langue:

english

Fichier:

PDF, 1.02 MB

english, 2014

Antiviral Potential of ERK/MAPK and PI3K/AKT/mTOR Signaling Modulation for Middle East Respiratory Syndrome Coronavirus Infection as Identified by Temporal Kinome Analysis

Kindrachuk, Jason, Ork, Britini, Hart, Brit J., Mazur, Steven, Holbrook, Michael R., Frieman, Matthew B., Traynor, Dawn, Johnson, Reed F., Dyall, Julie, Kuhn, Jens H., Olinger, Gene G., Hensley, Lisa

Journal:

Antimicrobial Agents and Chemotherapy

Année:

2015

Langue:

english

Fichier:

PDF, 1.62 MB

english, 2015

Enhanced potency of a fucose-free monoclonal antibody being developed as an Ebola virus immunoprotectant

Larry Zeitlin, James Pettitt, Corinne Scully, Natasha Bohorova, Do Kim, Michael Pauly, Andrew Hiatt, Long Ngo, Herta Steinkellner, Kevin J. Whaley and Gene G. Olinger

Journal:

Proceedings of the National Academy of Sciences

Année:

2011

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2011

Role of EXT1 and Glycosaminoglycans in the Early Stage of Filovirus Entry

O'Hearn, Aileen, Wang, Minxiu, Cheng, Han, Lear-Rooney, Calli M., Koning, Katie, Rumschlag-Booms, Emily, Varhegyi, Elizabeth, Olinger, Gene, Rong, Lijun, García-Sastre, A.

Journal:

Journal of Virology

Année:

2015

Langue:

english

Fichier:

PDF, 1.46 MB

english, 2015

Protective Role of Cytotoxic T Lymphocytes in Filovirus Hemorrhagic Fever

Warfield, Kelly Lyn, Olinger, Gene Garrard

Journal:

Journal of Biomedicine and Biotechnology

Année:

2011

Langue:

english

Fichier:

PDF, 173 KB

english, 2011

Aerosol Exposure to Rift Valley Fever Virus Causes Earlier and More Severe Neuropathology in the Murine Model, which Has Important Implications for Therapeutic Development

Reed, Christopher, Lin, Kenny, Wilhelmsen, Catherine, Friedrich, Brian, Nalca, Aysegul, Keeney, Ashley, Donnelly, Ginger, Shamblin, Joshua, Hensley, Lisa E., Olinger, Gene, Smith, Darci R., de Silva,

Journal:

PLoS Neglected Tropical Diseases

Année:

2013

Langue:

english

Fichier:

PDF, 3.84 MB

english, 2013

Gene-Specific Countermeasures against Ebola Virus Based on Antisense Phosphorodiamidate Morpholino Oligomers

Warfield, Kelly L., Swenson, Dana L., Olinger, Gene G., Nichols, Donald K., Pratt, William D., Blouch, Robert, Stein, David A., Aman, M. Javad, Iversen, Patrick L., Bavari, Sina

Journal:

PLoS Pathogens

Année:

2006

Langue:

english

Fichier:

PDF, 422 KB

english, 2006

Ebola Virus Inactivation with Preservation of Antigenic and Structural Integrity by a Photoinducible Alkylating Agent

Warfield, Kelly L., Swenson, Dana L., Olinger, Gene G., Kalina, Warren V., Viard, Mathias, Aitichou, Mohamed, Chi, Xiaoli, Ibrahim, Sofi, Blumenthal, Robert, Raviv, Yossef, Bavari, Sina, Aman, M. Java

Journal:

The Journal of Infectious Diseases

Année:

2007

Langue:

english

Fichier:

PDF, 387 KB

english, 2007

Long-term sequelae after Ebola virus disease in Bundibugyo, Uganda: a retrospective cohort study

Clark, Danielle V, Kibuuka, Hannah, Millard, Monica, Wakabi, Salim, Lukwago, Luswa, Taylor, Alison, Eller, Michael A, Eller, Leigh Anne, Michael, Nelson L, Honko, Anna N, Olinger, Gene G, Schoepp, Ran

Journal:

The Lancet Infectious Diseases

Année:

2015

Langue:

english

Fichier:

PDF, 190 KB

english, 2015

Inhibition of Ebola and Marburg viral entry by G protein-coupled receptor antagonists

Cheng, Han, Lear-Rooney, Calli M., Johansen, Lisa, Varhegyi, Elizabeth, Chen, Zheng W., Olinger, Gene G., Rong, Lijun

Journal:

Journal of Virology

Année:

2015

Langue:

english

Fichier:

PDF, 3.40 MB

english, 2015

Lack of Effect of Lamivudine on Ebola Virus Replication

Hensley, Lisa E., Dyall, Julie, Olinger, Gene G., Jahrling, Peter B.

Journal:

Emerging Infectious Diseases

Année:

2015

Langue:

english

Fichier:

PDF, 566 KB

english, 2015

Filovirus‐Like Particles Produced in Insect Cells: Immunogenicity and Protection in Rodents

Warfield, Kelly L., Posten, Nichole A., Swenson, Dana L., Olinger, Gene G., Esposito, Dominic, Gillette, William K., Hopkins, Ralph F., Costantino, Julie, Panchal, Rekha G., Hartley, James L., Aman, M

Journal:

The Journal of Infectious Diseases

Année:

2007

Langue:

english

Fichier:

PDF, 386 KB

english, 2007

Viral Hemorrhagic Fever Diagnostics

Racsa, Lori D., Kraft, Colleen S., Olinger, Gene G., Hensley, Lisa E.

Journal:

Clinical Infectious Diseases

Année:

2015

Langue:

english

Fichier:

PDF, 991 KB

english, 2015

The lipid moiety of brincidofovir is required for in vitro antiviral activity against Ebola virus

McMullan, Laura K., Flint, Mike, Dyall, Julie, Albariño, Cesar, Olinger, Gene, Foster, Scott, Sethna, Phiroze, Hensley, Lisa E., Nichol, S.T., Lanier, E. Randall, Spiropoulou, Christina F.

Journal:

Antiviral Research

Année:

2015

Langue:

english

Fichier:

PDF, 2.90 MB

english, 2015

Antibody therapeutics for Ebola virus disease

Zeitlin, Larry, Whaley, Kevin J, Olinger, Gene G, Jacobs, Michael, Gopal, Robin, Qiu, Xiangguo, Kobinger, Gary P

Journal:

Current Opinion in Virology

Année:

2016

Langue:

english

Fichier:

PDF, 379 KB

english, 2016

Targeting biodefense markets

Olinger Jr., Gene Garrard

Journal:

Human Vaccines

Année:

2009

Langue:

english

Fichier:

PDF, 836 KB

english, 2009

Association of indicators of bacterial vaginosis with a female genital tract factor that induces expression of HIV-1

Olinger, Gene G., Hashemi, Farhad B., Sha, Beverly E., Spear, Gregory T.

Journal:

AIDS

Année:

1999

Fichier:

PDF, 184 KB

1999

Human Antibodies to Major Histocompatibility Complex Alloantigens Mediate Lysis and Neutralization of HIV-1 Primary Isolate Virions in the Presence of Complement

Spear, Gregory T., Olinger, Gene G., Saifuddin, Mohammed, Gebel, Howard M.

Journal:

JAIDS Journal of Acquired Immune Deficiency Syndromes

Année:

2001

Fichier:

PDF, 646 KB

2001

Association of indicators of bacterial vaginosis with a female genital tract factor that induces expression of HIV-1

Olinger, Gene G., Hashemi, Farhad B., Sha, Beverly E., Spear, Gregory T.

Journal:

AIDS

Année:

1999

Langue:

english

Fichier:

PDF, 184 KB

english, 1999

Human Antibodies to Major Histocompatibility Complex Alloantigens Mediate Lysis and Neutralization of HIV-1 Primary Isolate Virions in the Presence of Complement

Spear, Gregory T., Olinger, Gene G., Saifuddin, Mohammed, Gebel, Howard M.

Journal:

JAIDS Journal of Acquired Immune Deficiency Syndromes

Année:

2001

Fichier:

PDF, 646 KB

Abdulla, Aynur, Wang, Boqian, Qian, Feng, Kee, Theodore, Blasiak, Agata, Ong, Yoong Hun, Hooi, Lissa, Parekh, Falgunee, Soriano, Rafael, Olinger, Gene G., Keppo, Jussi, Hardesty, Chris L., Chow, Edwar

Journal:

Advanced Therapeutics

Année:

2020

Fichier:

PDF, 2.54 MB

2020